Hairy leukoplakia of tongue

Vera. Age: 21.
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In immunocompromised subjects, Epstein-Barr virus EBV infection of terminally differentiated oral keratinocytes may result in subclinical productive infection of the virus in the stratum spinosum and in the stratum granulosum with shedding of infectious virions into the oral fluid in the desquamating cells. In a minority of cases this productive infection with dysregulation of the cell cycle of terminally differentiated epithelial cells may manifest as oral hairy leukoplakia. This is a white, hyperkeratotic, benign lesion of low morbidity, affecting primarily the lateral border of the tongue.

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Malaysia. Age: 25.
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Oral Hairy Leukoplakia

It is rare in HIV-negative patients, but has been reported in patients who use immune-modulating medications e. The objectives of this study were to determine the occurrence of OHL in HIV-negative patients and report Langerhans cell counts in these lesions. Langerhans cells were counted using an immunoperoxidase stain for CD1a and light microscopy. Results: The 7 patients were male, ranging in age from 26 to 69 years.

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Cecilia. Age: 23.
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Whitish Papules and Plaques on the Tongue

A year-old white man who had tested positive for human immunodeficiency virus HIV presented with a two-year history of white papules and plaques on the lateral borders of his tongue Figures 1 and 2. There were no lesions on the palate, the inner aspect of the cheeks, or the lips. The patient reported a history of smoking for several years.

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The symptoms of oral hairy leukoplakia may look like other medical conditions or problems. Always talk with your healthcare provider for a diagnosis. Oral hairy leukoplakia patches are easy to identify.